人才队伍

2001.09-2005.07，武汉大学，化学与分子科学学院，理学学士；

2005.09-2010.06：中科院理化所，有机化学专业，理学博士；

2010.07-至今，中科院理化所，历任助理研究员、副研究员、研究员、博士生导师。

长期从事光化学、光物理相关的基础及应用研究，主要包括：

（1） 光诊疗：发展新型高效及高选择性光动力抗肿瘤及抗菌光敏药物；

（2） 光/电化学合成：发展高附加值精细化学品的绿色低碳合成新方法及放大工艺。

1）Chao Zhang,# Jia Huang,# Xusheng Guo, Xuwen Da, Zhifei Dai, Moustapha Hassan, Yingjie Yu,* Xuesong Wang,* Qianxiong Zhou,* NIR light-driven photocatalytic NAD(P)H oxidation and H₂O₂ generation in situ for enhanced chemodynamic therapy and immune response, Nano Today, 2023, 50, 101824.

2) Na Tian, Weize Sun, Yang Feng, Xusheng Guo, Jian Lu, Chao Li, Yuanjun Hou, Xuesong Wang*, Qianxiong Zhou*, Chloromethyl-modified Ru(II) complexes enabling large pH jumps at low concentrations through photoinduced hydrolysis, Chem. Sci., 2019, 10, 9949-9953.

3）Xuwen Da, Xiulian Liu, Chao Li, Yatong Peng, Yao Jian, Wanpeng Zhou, Yunli Xu, Yao Wu, Xuesong Wang,* Qianxiong Zhou,* Ru/Pt@BSA nanoparticles for efficient photo-catalytic oxidation of NAD(P)H and targeted cancer treatment under hypoxic conditions, Chin. Chem. Lett., 2023, 34, 108317.

4）Wanpeng Zhou, Xuwen Da, Yunli Xu, Yatong Peng, Xiulian Liu, Yao Wu, Yu Shi, Aifeng Wu, Yishan Yao,* Xuesong Wang,* Qianxiong Zhou,* HClO-responsive dinuclear Ru(II) complexes for selective imaging and efficient photo-inactivation of intracellular bacteria, Chin. Chem. Lett., 2025, 36, 110376.

5）Weize Sun,# Yao Jian,# Mengxue Zhou, Yishan Yao, Na Tian, Chao Li, Jun Chen, Xuesong Wang,* Qianxiong Zhou,* Selective and efficient photo-inactivation of intracellular Staphylococus aureus and MRSA with little accumulation of drug resistance: an application of a Ru(II) complex with photolabile ligands, J. Med. Chem. 2021, 64, 7359-7370.